First generation of a small chemical molecule ROR1 RTK tyrosine kinase inhibitor
نویسندگان
چکیده
منابع مشابه
construction and stable expression of a truncated human receptor tyrosine kinase ror1 (ror1-ecd)
expression of receptor tyrosine kinase ror1 in a wide variety of cancers has emerged as a new era focusing on targeting this receptor in cancer therapy. our preliminary re-sults indicate the presence of a truncated transcript of ror1 in tumor cells. the trun-cated ror1 encompasses extracellular and transmembrane domains, lacking catalytic kinase domain (ror1-ecd). as enzyme activity is highly d...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2016
ISSN: 0923-7534
DOI: 10.1093/annonc/mdw392.15